Felodipine

Felodipine is a long acting calcium channel blocker type which is used to treat hypertension and stable angina. It was first patented in 1978 used since 1988.

It is used alone or in combination with other drugs (candesartan, ramipril, enalapril and metoprolol) for hypertension. The antihypertensive effects takes 2–5 hours to occur.

Mechanism of action: calcium channel blocker

Interaction: avoid grapefruit products; severe interaction with dantrolene and itraconazole

Side Effects:
Common: ankle oedema in around 10%; appears 2-3 weeks after starting the drug
Less common: facial flushing, heart palpitations, headache, dizziness and fatigue.

Brand names: Plendil (Astra Zeneca), Cardioplen, Folpik
Chemical formula: C18H19Cl2NO4

Other calcium channel blockers:

DihydropyridinesPhenylakylaminesBenzothiazepines
NifedipineVerapamilDiltiazem
Amlodipine
Felodipine
Cilnidipine

Page last updated: Jun 17, 2022 @ 10:00 am

 
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