# Drug – Receptor Interactions

Wikis > Pharmacology > Pharmacodynamics > Drug – Receptor Interactions

Drug – Receptor Interactions:
Most drugs have their effect via acting through specific protein receptors to do the following:
1) Activate receptors  produce a response (agonists)
2) Associate with receptors  reduce change of other agents activating receptor (antagonist)
Drugs are initially attracted to receptor via a weak electrostatic charge – if shape of drug is compatible with receptor  chemical bonds

Affinity – refers to the strength of the attraction between the drug and its receptor