Benzodiazepines

Benzodiazepines:
• eg clonazepam, clorazepate, diazepam, lorazepam
• causes potentiation of GABA
• Clonazepam used for absence, tonic and myoclonic seizures
• Diazepam  status epilepticus
• adverse effects – CNS depression (drowsiness, fatigue); hyperactivity, aggression