Wikis > General Medicine > Endocrine & Metabolic Disorders > Adrenal/Suprarenal Gland > Adrenal Disorders > Hyperaldosteronism
Hyperaldosteronism:
Clinical syndrome resulting from excess aldosterone secretion by adrenal cortex, independent of the renin-angiotensin system.
Aetiology:
Primary – >50% due to adenoma of adrenal cortex (Conn’s syndrome; Primary aldosteronism)
Secondary – increased production of aldosterone from adrenal cortex – due to increased stimulus.
Clinical features:
Hypokalaemia, metabolic acidosis, hypertension, muscles weakness, excessive thirst, possible paresthesia’s
Management:
Depends on cause
If adenoma surgical resection
Aldosterone antagonist – spironolactone
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