Characterised by yellow/green discolouration. 2 of 3 cases have the 3 features of yellow nails, lymphoedema and pleural effusions (or other respiratory condition). Ankle oedema common. Family history rare. M > F. Nails grow slowly.
Discolouration may be due to poor lymphatic drainage or oxidation of lipid compounds in nail. Often also get longitudinal and transverse ridges – also exaggerated lateral curvature.
Associated with renal and respiratory abnormalities, malignancies, thyroid disease, rheumatoid arthritis
Treatment – symptomatic management of medical problems. Spontaneous resolution has been reported with resolution of systemic symptoms
https://rarediseases.org/rare-diseases/yellow-nail-syndrome/
https://www.ncbi.nlm.nih.gov/books/NBK557760/
https://dermnetnz.org/topics/yellow-nail-syndrome
https://ojrd.biomedcentral.com/articles/10.1186/s13023-017-0594-4
https://en.wikipedia.org/wiki/Yellow_nail_syndrome
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