Drugs that inhibit platelet activity

Drugs that inhibit platelet activity:

Platelet aggregation inhibitors affect the formation of the chemical signals that promote platelet aggregation.

Indicated for prophylaxis or arterial thrombosis and during treatment of myocardial infarction.

eg NSAID’s (including aspirin); sulphinpyrazone; dipyridamole; dextrans; dazoxiben; epoprostnol

NSAID’s inhibit the formation of TXA2 (thromboxane); dipyridamole decrease platelet adhesion to damaged endothelium

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