Meta-analysis:
Study of studies. An attempt to condense the results of several clinical trials.
Not to be confused with a systematic review of the literature.
Original data from all available studies are collected and analysed together as if they are one dataset this increases the power by the use of a larger sample size – also improves the estimate of effect size.
Issues:
• wisdom of combining results from studies that differ in many respects
• “publication bias” – only positive results tend to get published – negative studies may not be available for inclusion
http://www.students4bestevidence.net/meta-analysis-what-why-and-how/
Hilda Bastian: Should we trust meta-analyses with meta conflicts of interest?
https://sciencebasedmedicine.org/the-misuse-and-abuse-of-meta-analyses/
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