Big Bang Theory is an American sitcom based around the lives of 4 scientists and a waitress living in Pasadena, California. One of the key characters, Sheldon Cooper MA, MS, PhD, ScD, BS (Jim Parsons) is described by Wikipedia as:
Sheldon exhibits a strict adherence to routine, a total lack of social skills, a tenuous understanding of irony, sarcasm, and humor, a general lack of humility or empathy, and displays textbook narcissistic behavior.
In episode 15 of Season 5, 'The Friendship Contraction' (originally aired February 2, 2012), Sheldon's roommate Leonard Hofstadter (Johnny Galecki) suspends the roommate agreement that he has with Sheldon. This leaves Sheldon without someone to take him to the dermatologist, allergist or podiatrist.