Pituitary drugs

Pituitary drugs

Growth hormone:
• eg somatrem, somatropin
• relaces hormone secreted by anterior pituitary  stimulate linear growth
• indicated for pituitary dwarfism
• contraindicated – closed epiphyses
• adverse effects – glucose intolerance, gigantism with high doses

Antidiuretic hormones:
• desomopressin, vasopressin
• replace hormone secreted by posterior pituitary gland  enhance resorption of water in kidneys
• indications – diabetes insipidus, nocturnal enuresis
• adverse effects – water intoxication, hyponatraemia, abdominal cramps, nausea, hypertension

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