Parathyroid drugs

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Parathyroid drugs

Parathyroid drugs  increase serum calcium levels.
• eg calcitriol, calcium chloride, calcium gluconate, calcium carbonate
• Indications – hypercalcaemia, hypoparathyroidism, prevention and treatment of osteoporosis
• Adverse effects – hypercalcaemia (nausea, vomiting, anorexia, polyuria, polydipsia, constipation, arrhythmias, lethargy)

Antihypercalcaemic drugs  reduce serum calcium
• eg calcitonin, gallium nitrate
• indications – hypercalcaemia, Paget’s disease
• adverse effects – hypocalcaemia (nausea, vomiting, tetany, positive Trousseau’s sign, positive Chvostek’s sign)

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