Wikis > Pharmacology > Anticoagulant, antiplatelet, thrombolytic and antihemorrhagic drugs > Thrombolytic drugs > Alteplase
Alteplase (tPA):
• tissue plasminogen activator (tPA) – produced by recombinant DNA technology
• promotes conversion of plasminogen to plasmin digests fibrin matrix in clots
• indicated for acute myocardial infarction, pulmonary embolism
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