Wikis > Patient Assessment and Examination > Laboratory Tests > Rheumatological, Immunological and Inflammatory Tests > Antinuclear antibodies
Antinuclear antibodies (ANA’s):
Group of antibodies directed against nuclear components (eg DNA, DNP, RNA). Several tests available – immunofluoresence, immunoassay and immunodiffusions.
Testing indicated when autoimmune disease is suspected (not a good screening test).
Different profiles of ANA’s have been described and correlated to clinical features of diseases.
Present in 95% of systemic lupus erythematosus.
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