Mononeuropathy Multiplex

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Mononeuropathy Multiplex

Focal, acute, asymmetric involvement of one or more peripheral or cranial nerves.
Usually get pain and weakness.

May be related to a microangiopathy  nerve ischaemia (may be a factor in diabetes)
In late stage HIV, cytomegalovirus has been reported in the nerves.

Aetiology:
More common in diabetes mellitus; HIV infection; demyelinating neuropathies; vasculitis; granulomatosis diseases (eg sarcoidosis);

Clinical features:
Depends on nerve; usually pain and weakness.
Foot drop can occur

Management:
Treatment of underlying cause; physical therapy for pain

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