Motor Neuron Disease

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Motor Neuron Disease

Diseases that cause loss of upper and/or lower motor neuron functions (mostly weakness and muscle wasting).

Classification:
1) Upper motor neuron diseases:
primary lateral sclerosis
spastic paresis
spastic paraplegia

2) Combined upper and lower motor neuron disease:
• amyotrophic lateral sclerosis (ALS)

3) Lower motor neuron disease:
• spinal muscular atrophies
• x-linked spinobulbar muscular atrophy
• poliomyelitis

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