Koch’s Postulates

Koch’s Postulates (1876):
1. The causative organism must be present in every case of the disease and not be present in healthy cases
2. The causative organism must be isolated from diseased cases and grown in culture
3. The same disease must be produced when the causative organism is inoculated into healthy cases
4. The same causative organism must be recoverable from the inoculated cases and grown in culture

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