Wikis > Microbiology and Infection Control > Defence against infection > Immune Response / “Third line of defence” > Cells and molecules of the immune system > Monokines
Monokines (released by macrophages):
• interleukin 1 (Il-1) – stimulates T and B cells to proliferate; causes fever (resets ‘thermostat’ of hypothalamus
• tumour necrosis factor (TNF) – kills cells; helps activate T cells, phagocytes and eosinophils; damages blood vessels
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