Crystal Induced Arthritides
Gout:
Erosions with a sclerotic margin and an overhanging edge (from tophus deposits expanding into bone bone reaction sclerotic margin)
Joint space usually normal until late in disease
Relative lack of periarticular osteoporosis for the amount of erosion present
Nodules in soft tissues
Early – soft tissue swelling; typically asymmetric; oedema of soft tissues
Intermediate – punched out bone lesions become sclerotic as increase in size
Late – interosseous tophi; joint space narrowing; deformity and subluxation
CPPD/Pseudogout:
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