Non-Hodgkin’s Lymphoma

Wikis > General Medicine > Haematology > Malignancies > Lymphoma > Non-Hodgkin’s Lymphoma

Non-Hodgkin’s Lymphoma (NHL)/Lymphoma:
Annual incidence of 12/100 000; median age of onset 65-70yrs

3 clinical forms based on lymph node biopsy
• low grade lymphomas
• intermediate grade lymphomas
• high grade lymphoma

Clinical features:
• Enlargement of lymph nodes – painless; solitary or diffuse; may be associated with splenomegaly
• Systemic features due to hypermetabolism form rapid turnover of cells – fatigue; malaise; fever; weight loss; pruritis; sweating; anaemia; infections
• Extranodal tumour spread

Comments are closed.