Wikis > General Medicine > Haematology > Haemostasis and Blood Coagulation > Bleeding Disorders > Haemophilia A
Haemophilia A:
Reduction of factor VIII; affects 1/10 000;
Sex linked inheritance; factor VIII gene in on the X chromosome
Clinical features:
Usually noticed after age 6 months – superficial bruising and/or haemoarthrosis
Management:
Bleeding episodes IV infusion of factor VIII concentrate
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