Diseases of stomach and duodenum
Manifested by pain; vomiting; bleeding; dyspepsia
Gastritis:
Most common stomach disorder.
Histological diagnosis – due to inflammation of the gastric mucosa.
Acute or chronic:
• acute – due to drugs (eg aspirin, NSAID’s, iron preparations); Helicobacter pylori; alcohol; viral infection; severe physiological stress (eg burns, multi-organ failure); irritating foot (eg hot peppers)
• chronic – due to autoimmune; Helicobacter pylori; tuberculosis; gastrointestinal disease (eg Crohn’s disease); sarcoidosis
Treatment – eliminate cause; symptomatic and supportive while healing takes place.
Peptic Ulcer:
Condition in which there is a discontinuity in the entire thickness of the gastric or duodenal mucosa. Can affect up to 10% of the population at some time. M2-5x>F.
Aetiology:
Helicobacter pylori infection (90%); NSAID toxicity (2nd most common reason); usually have family history hereditary component; stress, smoking, caffeine and alcohol increases risk
Clinical features:
Episodic pain – located near base of sternum – usually more severe at night; usually occurs 1-3 hours after meal; relived by antacids, milk or food;
Complications – perforation (contents of stomach escape into peritoneal cavity); gastric outlet obstruction; bleeding
Management:
Lifestyle changes (stop smoking; relaxation; etc); antibiotics and proton pump inhibitor (eg omeprazole) for Helicobacter pylori infection; avoid aspirin and NSAID’s; antacids; histamine H2-receptor antagonist drugs (eg cimetidine); H+/K+ATPase (proton pump) inhibitors; surgical – partial gastrectomy
We have not yet got to this page. We will eventually. Please contact us if you have something to contribute to it or sign up for our newsletter or like us on Facebook and Instagram or follow us on Twitter. |
Page last updated:
Comments are closed.