Inflammation of thyroid.
1) Silent lymphocytic thyroiditis
2) Subacute thyroiditis (granulomatous, giant cell, or de Quervain’s Thyroiditis)
3) Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis, autoimmune thyroiditis)
Common cause of hypothyroidism. Common in several collagen vascular diseases (eg SLE, rheumatoid arthritis, MCTD). Typically females aged 20 to 60yrs.
Associated with HLA-B8, DR3
Subacute/de Quervain’s thyroiditis:
Viral induced inflammation. Pain in region of gland that may radiate to jaw. Thyroid hormone levels are raised.