Osteonecrosis/avascular necrosis/aseptic necrosis

Wikis > General Medicine > Bone Disorders > Osteonecrosis/avascular necrosis/aseptic necrosis

Osteonecrosis/avascular necrosis/aseptic necrosis:

Focal necrosis/death of bone (osteocytes) and bone marrow – related to ischaemia. Most commonly femoral head. In foot – talus, navicular and metatarsals are most commonly affected.

Traumatic disruption of blood supply; corticosteroid use (50% of nontraumatic cases) haemoglobinopathies; Cushing’s disease; renal transplant; pancreatitis; alcoholism; collagen disorders (eg SLE); thermal injuries; hyperuricaemia

Clinical features:
Pain – often sudden onset – exacerbated by weightbearing – may be present at rest.
Tender to palpation; normal joint range of motion



Comments are closed.