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P value ban: small step for a journal, giant leap for science
http://www.nature.com/news/scientific-method-statistical-errors-1.14700
We’re using a common statistical test all wrong. Statisticians want to fix that.
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Clinical and Statistical Significance
Statistically significant finding is a conclusion that there is evidence against the null hypothesis.
A ‘significant’ finding means that the difference was probably caused by something other than chance
A small difference between two large groups can be statistically significant but have little clinical meaning.
A large difference between two small groups can be clinically significant but not statistically significant.
When considering the significance reported in a study, consider:
• how likely is the significant difference due to chance (a type 1 error)
• if it was not due to chance, how likely was it due to flaws or biases in the study
• how likely was a type 2 error if the difference was not statistically significant
• if the differences are statistically different, are they also clinically significant
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