Wikis > Pharmacology > Drugs Acting on the Autonomic Nervous System > Adrenergic Drugs > Indirect acting antiadrenergic agents > Guanethidine
Guanethidine:
• similar effects to reserpine, but can not cross blood-brain barrier no CNS effects
• taken up by adrenergic neurons blocks norepinephrine release and deplete storage vesicles
• used for hypertension
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