Prion diseases (previously known as transmissible spongiform encephalopathy)
Fatal neurodegenerative diseases affecting both human and non-human mammals
The word “prion” (given by Stanley B. Prusiner in 1982) comes from “proteinaceous infectious particle”.
Prion diseases are extremely rare with an annual mortality rate of approximately one to two per million
Creutzfeldt-Jakob disease (CJD) is the most common human prion disease worldwide,
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