Progressive multifocal leukoencephalopathy (PML):
Often seen in AIDS and other immunosuppressive conditions (eg cancer patients; transplant recipients); opportunistic viral (papovavirus JC or SV-40) infection of the oligodendrocytes demyelination of white matter in CNS; in 4-5% of those infected with HIV; in those with HIV, this is initial feature of AIDS in 25%; onset insidious of focal neurological signs (dementia, apraxia, ataxia, blindness); hemiparesis is most common initial feature; progresses to global impairments and death in 3-20 months; no effective treatment (cytosine arabinoside may have marginal benefits).
We have not yet got to this page. We will eventually. Please contact us if you have something to contribute to it or sign up for our newsletter or like us on Facebook and Instagram or follow us on Twitter. |
Page last updated:
Comments are closed.