Acute disseminated encephalomyelitis:
Postinfectious autoimmune demyelination of brain and spinal cord; usually develops 4-6 days after viral infection (eg measles, chicken pox, rubella) or 10-15 days after vaccination (eg smallpox, rubella); if mild headache, stiff neck, fever, confusion; if severe convulsions, quadriplegia, cranial nerve palsies, sensory loss; 10-50% mortality; 25-50% left with severe neurological features; corticosteroids reduce severity
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